CAS NO.: 4192-90-9
Molecular Formula: C21H24O10
Molecular Weight: 436.4
Solubility : 0.7 g/L at 25°C
It is a dihydrochalcone type natural sweetener extracted from the Lithocarpus litseifolius (sweet tea) plant. It has no calories and has the function of lowering blood sugar.
Lowering blood sugar: Trilobatin has been shown to inhibit the activity and antioxidant properties of key enzymes in diabetes (α-glucosidase and α-amylase), inhibit insulin resistance, and improve complications mediated by hyperglycemia. It is a precious plant that can be used as both medicine and food, and has three functions: tea, sugar and medicine.
Liver protection and anti-inflammation: Trilobatin can significantly inhibit the secretion of TNF-α and IL-6 in the serum of LPS-induced samples, reduce the expression levels of TNF-α and IL-6 in liver tissue, and has a significant anti-inflammatory effect.
Anti-cancer: Trilobatin has a significant inhibitory effect on gefitinib-resistant lung cancer cells, mainly by inhibiting the NF-kB signaling pathway, thereby inducing apoptosis of lung cancer cells.