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Trilobatin
Trilobatin
Trilobatin
Trilobatin
Trilobatin
Trilobatin
Trilobatin
Trilobatin
Trilobatin
Trilobatin

Trilobatin

CAS NO.: 4192-90-9

Molecular Formula: C21H24O10

Molecular Weight: 436.4

Solubility : 0.7 g/L at 25°C

 

It is a dihydrochalcone type natural sweetener extracted from the Lithocarpus litseifolius (sweet tea) plant. It has no calories and has the function of lowering blood sugar.

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Product Features

  1. The sweetness of trilobatin is 300 times that of sucrose. It is a natural sweetener with high sweetness and no calories. The sweetness is refreshing and pure, with a faint tea flavor and sweet aftertaste. It can be used as food enhancer.
  2. After compounding with erythritol, isomalt, maltitol and other polysaccharide alcohols, the sweetness, taste and flavor characteristics can be similar to that of sucrose.
  3. Non hygroscopic, non deliquescent, good stability, easily soluble in hot water and ethanol, solubility in water at room temperature 25°C is 0.7g/L.
  4. Health functional food

Lowering blood sugar: Trilobatin has been shown to inhibit the activity and antioxidant properties of key enzymes in diabetes (α-glucosidase and α-amylase), inhibit insulin resistance, and improve complications mediated by hyperglycemia. It is a precious plant that can be used as both medicine and food, and has three functions: tea, sugar and medicine.

Liver protection and anti-inflammation: Trilobatin can significantly inhibit the secretion of TNF-α and IL-6 in the serum of LPS-induced samples, reduce the expression levels of TNF-α and IL-6 in liver tissue, and has a significant anti-inflammatory effect.

Anti-cancer: Trilobatin has a significant inhibitory effect on gefitinib-resistant lung cancer cells, mainly by inhibiting the NF-kB signaling pathway, thereby inducing apoptosis of lung cancer cells.

Application

  • World Health Organization and Food and Agriculture Organization of the United Nations: Included in the Joint Expert Committee on Food Additives (JECFA) (#2171).
  • Listed as Generally Recognized as Safe (GRAS) (#4674) by FEMA.
  • As a flavoring substance in EU Regulation (EU) No 872/2012.
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