DeepSeek Analysis: Technological Attributes and Innovation Capabilities of Shandong Benyue Biotechnology

Shandong Benyue Biological Technology Co., Ltd

As a benchmark enterprise in synthetic biology in China, Shandong Benyue Biotechnology Co., Ltd. is driven by the “Chemistry +, Biology +” dual-core technology platform. Through the collaborative innovation of industry, academia, and research, as well as large-scale production, it has demonstrated remarkable technological attributes and innovation capabilities in the fields of bio-based materials and natural sweeteners.

Its market performance is also remarkable. Since it was listed on the innovation layer of the New Third Board in 2023, its sales have increased steadily with the help of the capital market to accelerate R&D and upgrading, and it is deeply trusted by customers across the country. Meanwhile, Shandong Benyue has been constantly innovating production technologies, evolving from a leader to one of the sweetener industry’s founders, leading the sweetener industry’s transformation and progress.

How has Shandong Benyue Biotechnology established its technological attributes by virtue of these advantages? Next, let’s have an in-depth insight through DeepSeek, which is a pride of domestic technology.

The following is a screenshot of DeepSeek’s response to questions related to “the technological attributes and innovation capabilities of Shandong Benyue Biotechnology Co., Ltd.” Through DeepSeek’s in-depth search and analysis, we found that in the sweetener field, Shandong Benyue Biotechnology ranks firmly among the top players in the sweetener industry in terms of technological leadership, the right to speak in industry standards and market reputation. Relying on the concept of “Chemistry +, Biology +,” it not only defines the product value but also promotes improving quality and efficiency in China’s sweetener industry. It is an optimal cooperation partner for the food industry to enhance efficiency.

The following is the text transcript: DeepSeek:

1. Company profile. It mentions that they belong to the field of biological manufacturing, with two core technology platforms, “Chemistry +” and “Biology +.” Their products include synthetic biology glycosidases, natural sweeteners, etc. They have 40 patents and recognition as a high-tech enterprise. This information should be used to showcase their core technology platforms and patent achievements.
2. Then there is Webpage 2 regarding the approval of the Shandong Provincial Engineering Research Center. This demonstrates their R & D strength, especially the high-performance bio-fermentation process, indicating their advantages in the field of biosynthesis. The importance of this research center can be emphasized.
3. Webpage 3 mentions the company’s annual production capacity, such as 500 tons of neotame and 200 tons of hesperidin. These production capacity data can highlight their large-scale production capabilities and market share situation. However, some of the data in the user’s previous reply may need to be confirmed.
4. Webpage 9 details the application of neo hesperidin, showing the application of the product in the pharmaceutical and food fields, which can be combined with their product innovation part.
5. Regarding the core technology platforms, the “Chemistry +” and “Biology +” dual platforms on page 1, the patent and standard setting, and the Engineering Research Center on page 2 can be combined to illustrate the technological R&D strength.
6. In terms of industry-university-research cooperation, the cooperation between the subsidiary Qingdao Benyue and professors, the zebrafish evaluation platform mentioned on page 1, the university alliances on Webpage 2, and the recruitment information on pages 8 and 10 indicating team building can all illustrate collaborative innovation.
7. In–depth Analysis of the Technological Attributes and Innovation Capabilities of Shandong Benyue Biotechnology Co., Ltd.

As a benchmark enterprise in the field of synthetic biology in China, Shandong Benyue Biotechnology Co., Ltd. (Stock Code: 873255) is driven by the “Chemistry +, Biology +” dual-core technology platform. Through the collaborative innovation of industry, academia, and research, as well as large-scale production, it has demonstrated remarkable technological attributes and innovation capabilities in the fields of bio-based materials and natural sweeteners. The following analysis is carried out from the dimensions of core technologies, product matrix, and innovation ecosystem:

I. Core Technologies: R & D System Driven by Synthetic Biology

1. “Chemistry +, Biology +” Dual-core Technology Platform

Relying on synthetic biology technology, the company has constructed an R & D system that deeply integrates chemical synthesis and biotransformation. Focusing on cutting-edge technologies such as enzyme catalysis and genetic engineering, it has achieved the efficient production of natural sweeteners (such as steviol glycoside RM and hesperidin), significantly reducing costs and improving purity.

2. Patent Layout and Standard Leadership

As of 2024, the company has applied for a total of 40 patents (16 authorized invention patents), and has led or participated in the formulation of 1 national mandatory standard, 1 national recommended standard, and 2 industry group standards, promoting the standardized development of the industry. In addition, the “Shandong Provincial Engineering Research Center for R & D and Industrialization of High – performance Bio – Bio-fermentation Processes,” approved in 2024, has further consolidated its leading position in the field of bio-fermentation.

II. Product Innovation: Dual Breakthroughs in Health and Sustainability

1. Large-scale Production of Natural and Artificial Sweeteners

Benyue Biotechnology is one of the few enterprises in the world that can produce hesperidin (200 tons) and neotame (annual production capacity of 500 tons) on a large scale, with a domestic market share of over 50%. Products such as steviol glycoside RM (future production capacity of 2000 tons) and naringin are exported to more than 20 countries, including Germany, Spain, and the Netherlands. Its products replace traditional sugars and are widely used in low-sugar foods, beverages, and the pharmaceutical field, conforming to the global sugar-reduction trend.

2. Diversified Development of Bioactive Raw Materials

Centering on the active ingredients of the citrus genus, the company has developed raw materials such as A – glucosyl hesperidin and phloretin, which are applied to anti-glycation skin care products and functional foods, covering the large – health industry chain. For example, neohesperidin, as a key ingredient in gastrointestinal drugs, has passed the European Pharmacopoeia certification.

3. Exploration of Bio-based Materials

Combined with synthetic biology technology, the company is researching and developing new bio-based materials and is committed to promoting green chemical engineering and sustainable development.

III. Industry – University – Research Collaboration: Building an Open Innovation Ecosystem

1. University – affiliated Joint Laboratories

The company has cooperated with universities such as South China University of Technology and Jiangnan University to establish R&D centers, focusing on extracting functional components and optimizing enzyme-catalysis processes, accelerating the transformation of technological achievements.

2. Zebrafish Bioactivity Evaluation Platform

The subsidiary Qingdao Benyue Biotechnology uses the zebrafish model to evaluate raw materials’ bioactivity and safety quickly. It provides research assistance for scientific research, toxicology, and pharmacology testing in the fields of medicine, functional foods, health foods, and medical disease models, shortens the product and clinical R & D cycle, and improves product accuracy.

3. Talent and Team Building

The company was jointly founded by Shanyou Benyue and four professors. It has recruited more than 30 master’s and doctoral students in the fields of biosynthesis and fermentation engineering. Scientific research personnel account for more than 30% of the company’s staff, and the team’s innovation ability is strengthened through technical process training. Specifically, Shandong Province has a post-doctoral innovation practice base and major scientific and technological achievements.

IV. Qualifications and Honors: Endorsement of Technological Strength

1. It has been rated as a national high-tech enterprise thrice (2017 – 2023), demonstrating continuous R&D investment and technological barriers.
2. The titles of “Gazelle Enterprise” and “Specialized, Sophisticated, Differentiated and New Enterprise” in Shandong Province highlight its high growth potential and industry competitiveness.
3. It was listed on the innovation layer of the New Third Board in 2024, using the capital market to accelerate R&D and upgrading.

V. Future Layout: New Drivers of Biological Manufacturing

Under the “New and Old Kinetic Energy Conversion” strategy of Shandong Province, Benyue Biotechnology takes high-performance bio-fermentation processes as the core and accelerates the application of synthetic biology in food, pharmaceutical, and other fields. Its layout in the research and development of new bio-based materials and natural active ingredients is expected to become a new growth pole of the green economy. In addition, the company actively responds to the future industrial planning of Shandong Province, explores cutting-edge technologies such as gene editing and bio-breeding, and strengthens the deep integration of the innovation chain and the industrial chain.

Conclusion

Shandong Benyue Biotechnology, with the two-wheel model of technology-driven and industrial transformation, has not only reshaped the competition pattern of the sweetener industry but also opened up a new path of domestic substitution and sustainable development through synthetic biology technology. Driven by policy support and market demand, its technological attributes and innovation capabilities will continuously release industrial value, contributing to realizing the “Healthy China” and “Dual Carbon” goals.

(Data sources: Corporate official website, Shandong Provincial Development and Reform Commission, Qilu Talent Network, etc.)

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